Post Thumb

Cultura Colectiva +

Share it

VADIM FEDOROV, THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER. In humans, the heart’s sinoatrial node, acts as the body’s pacemaker. A new study, published Wednesday in Science Translational Medicine, reports two backup mechanisms that may prevent heart failure when the organ is faced with arrhythmia.

When the researchers added adenosine, a molecule involved in heartbeat rhythmicity that is produced in high quantities during ischemia and heart failure, they discovered two backup pacemaker mechanisms in the “Head” and “Tail” regions of the SAN. “The central pacemaker was most affected, as it is highly sensitive to adenosine. The head and tail pacemakers were able to maintain a slower rhythm and prevent complete cardiac arrest. We saw similar shifts in the preferred conduction pathways,” study coauthor Vadim Fedorov says the release.

Additional molecular analyses revealed different levels of two cardiac proteins, A1R and GIRK1/4, in the different SAN regions. The researchers think these may help regulate the activity of the backup pacemakers.

“Robustness-through functional, structural, and molecular redundancies-is an important property of the human SAN, which allows it to efficiently maintain its automaticity and conduction even during external and internal perturbations,” the authors write in the study.

“More detailed knowledge of the human SAN complex during normal and pathologic conditions is fundamental for the development of novel treatments for SAN arrhythmia.”

read more...

Article originally posted at www.facebook.com

Post Author: Chad Orzel

25 thoughts on “Cultura Colectiva +

    Joe Bear

    (October 29, 2017 - 12:06 pm)

    mo like radical fashion news

    Melanie Guthrie

    (October 29, 2017 - 12:06 pm)

    Kirby Welch…….should I?????

    Gabrielle Russell

    (October 29, 2017 - 12:06 pm)

    Kimberley Russell, can we try this? I know it’s a pain in the tuchas to lighten my hair enough to color it, but this looks soooooooo cool!

    Hugues Gontier

    (October 29, 2017 - 12:06 pm)

    Marion Frey on se chauffe pour le wei ? 😛

    Théo Van-b

    (October 29, 2017 - 12:06 pm)

    Léah tu devrais kiffer :p

    Meiko Lee

    (October 29, 2017 - 12:06 pm)

    Anna Ng I’m going to buy it xx

    John Grech

    (October 29, 2017 - 12:06 pm)

    Hey I can see you with this Fay Lim 😀

    Kevin Carlson

    (October 29, 2017 - 12:06 pm)

    UV fluorescent, will not glow by itself, needs black light

    Aditya Mall

    (October 29, 2017 - 12:06 pm)

    Now it will be easy to recognize Snowflakes in the dark.

    Kyle Ray

    (October 29, 2017 - 12:06 pm)

    Amanda Avers 🌝 it’s time

    Shawn Boyd

    (October 29, 2017 - 12:06 pm)

    Katelynn Doherty Brandon Boyd Francisco Erick Ponce

    Isabelle Choudhry

    (October 29, 2017 - 12:06 pm)

    Beck Claire

    Sergio C Marín

    (October 29, 2017 - 12:06 pm)

    Roberto Guerrero Gutiérrez (Discos)

    Allen Rice

    (October 29, 2017 - 12:06 pm)

    Gwen Cronin-Prather

    Agustin Toselli

    (October 29, 2017 - 12:06 pm)

    Cin Mussi

    Solide Algo

    (October 29, 2017 - 12:06 pm)

    Sonia Séguin

    Ryan Gimenez

    (October 29, 2017 - 12:06 pm)

    Jessie Mary

    Yassine Sabri

    (October 29, 2017 - 12:06 pm)

    Samy Sabry

    Fatma Bekheet

    (October 29, 2017 - 12:06 pm)

    Marwa Bekheet

    Solide Algo

    (October 29, 2017 - 12:06 pm)

    Sabrina Séguin

    Solide Algo

    (October 29, 2017 - 12:06 pm)

    Carole Seguin

    Sunrose Billing

    (October 29, 2017 - 12:06 pm)

    Rachel Sava

    Matthew Beckner

    (October 29, 2017 - 12:06 pm)

    She Hulk

    Christian Mishel Wehbe

    (October 29, 2017 - 12:06 pm)

    Donna-Maria Abou Khalifé

    Thomas Dolarian

    (October 29, 2017 - 12:06 pm)

    Justine Garcia

Leave a Reply

Your email address will not be published. Required fields are marked *