Put 50 newborn worms in 50 separate containers, and they’ll all start looking for food at roughly the same time. Like members of other species, microscopic C. elegans roundworms tend to act like other individuals their own age. It turns out that the innate system that controls age-appropriate #behavior in a developing worm is not […]
Machine vision creates brain-behavior maps from more than 5000 hours of fruit fly videos
Psychology lessons from Yale study on trick or treaters using Michelle Obama, Hillary Clinton and Halloween studies by Dan Ariely, Ed Diener
Author Summary What are the neural signatures of consciousness? This is an elusive yet fascinating challenge to current cognitive neuroscience, but it takes on an immediate clinical and societal significance in patients diagnosed as vegetative and minimally conscious. In these patients, it leads us to ask whether we can test for the presence of these signatures in the absence of any external signs of awareness. Recent conceptual advances suggest that consciousness requires a dynamic balance between integrated and differentiated networks of information exchange between brain regions. Here we apply this insight to study such networks in patients and compare them to healthy adults. Using the science of graph theory, we show that the rich and diversely connected networks that support awareness are characteristically impaired in patients, lacking the ability to efficiently integrate information across disparate regions via well-connected hubs. We find that the quality of patients’ networks also correlates well with their degree of behavioural responsiveness, and some vegetative patients who show signs of hidden awareness have remarkably well-preserved networks similar to healthy adults. Overall, our research highlights distinctive network signatures of pathological unconsciousness, which could improve clinical assessment and help identify patients who are aware despite being uncommunicative.