New research suggests life on Earth became more diverse because of a change in biology related to stem cells, not just rising oxygen levels.
In an advance that could push cheap, ubiquitous solar power closer to reality, University of Michigan researchers have found a way to coax electrons to travel much further than was previously thought possible in the materials often used for organic solar cells and other organic semiconductors.
A diminutive protein prompts a closer look at DNA dark matter.
Cancer researchers today announced they have developed a way of sidelining one of the most dangerous “bad actors” in leukemia. Their approach depends on throwing a molecular wrench into the gears of an important machine that sets genes into motion, enabling cancer cells to proliferate.
The first clinical trials are slated to begin in the U.S. and Europe while others are stalled.
Once incurable diseases are now in the sights of doctors.
Lawrence Livermore National Laboratory (LLNL) scientists and engineers have developed a “brain-on-a-chip” device aimed at testing and predicting the effects of biological and chemical agents, disease or pharmaceutical drugs on the brain over time without the need
The big-ticket acquisition of genetic design company Cell Design Labs signals a coming wave of precision cures.
Gary Steinberg defied convention when he began implanting living cells inside the brains of patients who had suffered from a stroke
Expanded genetic alphabet could allow for the production of new protein-based drugs
An examination of 54 human brains suggests that adults don’t grow new neurons in the hippocampus, contrary to several widely accepted studies.
A new study reveals that individual genes can create many different versions of the molecular machinery that powers the cell.
Scientists have used CRISPR/Cas9 editing to knock out endogenous T-cell receptors and engineer killer T cells that only express cancer antigen-specific TCRs.
Engineered tissue containing human stem cells has allowed paraplegic rats to walk independently and regain sensory perception. The implanted rats also show some degree of healing in their spinal cords. The research, published in Frontiers in Neuroscience, demonstrates the great potential of stem cel…
A healthy heart beats about two billion times during a lifetime, thanks to the interplay of more than 10,000 proteins. Researchers from the Max Planck Institute of Biochemistry (MPIB) and the German Heart Centre at the Technical University of Munich (TUM) have now determined which and how many individual proteins are present in each type of cell in the heart. They have now compiled the first atlas of the healthy human heart, known as the cardiac proteome. The atlas will make it easier to identify differences between healthy and diseased hearts in future.
Researchers at the MRC Weatherall Institute of Molecular Medicine have developed a new platform based on the revolutionary CRISPR/Cas9 technology, to alter the way human cells respond to external signals, and provide new opportunities for stopping cancer cells from developing.
An anti-aging strategy that works in mice is about to be tested in humans
Scientists are altering a powerful gene-editing technology in hopes of one day fighting diseases without making permanent changes to people’s DNA.
The blueprint for everything.
And she isn’t the only one.
Scientists from MIT and other institutions have developed a microfluidic device that uses sound waves to isolate cellular packets called exosomes from blood samples, which could be used to diagnose diseases such as cancer or fetal abnormalities.
Scientists have created a synthetic organism that possesses only the genes it needs to survive. But they have no idea what roughly a third of those genes do.
Hydrodynamics and competition guide the architectural design of biofilm fortresses.
Up until now, it’s only been possible to track where cells are in their life cycle once they’re dead. However, a new study outlines a method of analysing living cells by taking a close look at their nucleus.
A group of researchers at Columbia University’s School of Engineering and Applied Science have successfully developed the first functional vascularised lung scaffold, and it could dramatically change how lung disease is treated.
Lab tests only, so far
And could one day apply the buffers.
Nanomachines which can drill into cancer cells, killing them in just 60 seconds, have been developed by scientists. The tiny spinning molecules are driven by light, and spin so quickly that they can burrow their way through cell linings when activated. In one test conducted at Durham University the nanomachines
Scientists at the University of Oxford have developed a new method to 3D-print laboratory- grown cells to form living structures.
Researchers at The Ohio State University Wexner Medical Center and Ohio State’s College of Engineering have developed a new technology, Tissue Nanotransfection (TNT), that can generate any cell type of interest for treatment within the patient’s own body. This technology may be used to repair injured tissue or restore function of aging tissue, including organs, blood vessels and nerve cells.
Aging. We all face it. Nobody’s immune and we’ve long tried to reverse it, stop it or just even slow it down. While advances have been made, true age-reversal at a cellular level remains difficult to achieve. By taking a different approach, however, researchers at Houston Methodist made a surprising discovery leading to the development of technology with the ability to rejuvenate human cells. And that couldn’t be more important for the small population of children who are aging too quickly – children with progeria.
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The Francis Crick Institute is an interdisciplinary medical research institute.
The brain’s decline may mirror its beginning, offering clues to aging.
Once implanted into animals’ brains, neural stem cells that secrete microRNA-containing vesicles seem to contribute to an anti-aging effect.
Version of CAR T cell therapy could treat head and neck cancer, triple-negative breast cancer, pancreatic and ovarian cancers
Tissue “seeds” made up of three cell types and patterned onto a scaffold develop into complex structures with some organ function, researchers show.
Whether using embryonic or adult stem cells, coercing these master cells to convert to the desired target cell and reproduce flawlessly is difficult. Now an international team of researchers has a two-part system that can convert the cells to the targets and then remove the remnants of that conversion, leaving only the desired DNA behind to duplicate.
Scientists discover transcripts from the same gene that can express both proteins and noncoding RNA. Â
Age-associated B cells (ABCs) were discovered in 2011 to be phenotypically and functionally unique cells common in the spleen, blood, and bone marrow. Howe
New research reveals that HIV DNA can be excised from the genomes of living animals to eliminate further infection
Why do most patients fail to respond to the newest cures?
Drugs made from RNA may be the next great class of medicine.
Researchers have used two types of stem cells and a three dimensional scaffold to generate a structure like a mouse embryo. The researchers are hoping this
The dissection of how cells sense and propagate physical forces is leading to exciting new tools and discoveries in mechanobiology and mechanomedicine.
Mice models are more often than not the models of disease used to study the interaction between immune cells and cancer. A new study looks closer at whethe
JUPITER, FL – February 6, 2017 – The most frightening aspect of Zika virus has been its ability to produce severe fetal birth defects during pr
Gene Essential for Reprogramming Human Amniotic Stem Cells
Scientists have long known that DNA segments called telomeres play a crucial part in aging, but new research has discovered a protein that acts as a kind of cellular timekeeper, regulating the length of telomeres to maintain healthy cell division and prevent the development of cancer.
An experimental technology offers new hope to patients who have suffered severe burns.